CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

Enzyme Information

1.5.1.7
Saccharopine dehydrogenase (NAD(+), L-lysine-forming).
based on mapping to UniProt P38998
N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-lysine + 2-oxoglutarate + NADH.

UniProtKB Entries (1)

P38998
LYS1_YEAST
Saccharomyces cerevisiae S288C
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

PDB Structure

PDB 2QRK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Ligand-Bound Saccharopine Dehydrogenase from Saccharomyces cerevisiae
Andi, B., Xu, H., Cook, P.F., West, A.H.
Biochemistry