CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ribosomal protein S6 kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P18654
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P18654
KS6A3_MOUSE
Mus musculus
Ribosomal protein S6 kinase alpha-3

PDB Structure

PDB 2QR8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2.
Malakhova, M., Tereshko, V., Lee, S.Y., Yao, K., Cho, Y.-Y., Bode, A., Dong, Z.
Nat.Struct.Mol.Biol.