CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family 3-hydroxyanthranilate 3,4-dioxygenase

Enzyme Information

1.13.11.6
3-hydroxyanthranilate 3,4-dioxygenase.
based on mapping to UniProt P46952
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
-!- The product of the reaction spontaneously rearrange to quinolinic acid (quin). -!- Formerly EC 1.13.1.6.

UniProtKB Entries (1)

P46952
3HAO_HUMAN
Homo sapiens
3-hydroxyanthranilate 3,4-dioxygenase

PDB Structure

PDB 2QNK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Human 3-hydroxyanthranilate 3,4-dioxygenase.
Bitto, E., Bingman, C.A., Wesenberg, G.E., Phillips Jr., G.N.
to be published