CATH Classification

Domain Context

CATH Clusters

Superfamily Single helix bin
Functional Family

Enzyme Information

7.1.1.8
Quinol--cytochrome-c reductase.
based on mapping to UniProt Q02762
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3). -!- Formerly EC 1.10.2.2.

UniProtKB Entries (1)

Q02760
CY1_RHOSH
Rhodobacter sphaeroides
Cytochrome c1

PDB Structure

PDB 2QJY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Inhibitor-complexed Structures of the Cytochrome bc1 from the Photosynthetic Bacterium Rhodobacter sphaeroides.
Esser, L., Elberry, M., Zhou, F., Yu, C.A., Yu, L., Xia, D.
J.Biol.Chem.