CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family Metallo-beta-lactamase L1 type 3

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P52700
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P52700
BLA1_STEMA
Stenotrophomonas maltophilia
Metallo-beta-lactamase L1 type 3

PDB Structure

PDB 2QJS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Basis for the Role of Asp-120 in Metallo-beta-lactamases
Crisp, J., Conners, R., Garrity, J.D., Carenbauer, A.L., Crowder, M.W., Spencer, J.
Biochemistry