CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family Cytokinin dehydrogenase 7

Enzyme Information

1.5.99.12
Cytokinin dehydrogenase.
based on mapping to UniProt Q9FUJ1
N(6)-dimethylallyladenine + acceptor + H(2)O = adenine + 3-methylbut-2- enal + reduced acceptor.
-!- Converts zeatin and related cytokinins. -!- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is a dimethylallyl or other prenyl group. -!- Although this activity was previously thought to be catalyzed by a hydrogen-peroxide-forming oxidase, this enzyme does not require oxygen for activity and does not form hydrogen peroxide. -!- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium, phenazine methosulfate and Cu(2+) in the presence of imidazole can act as acceptors.

UniProtKB Entries (1)

Q9FUJ1
CKX7_ARATH
Arabidopsis thaliana
Cytokinin dehydrogenase 7

PDB Structure

PDB 2Q4W
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Arabidopsis thaliana cytokinin dehydrogenase.
Bae, E., Bingman, C.A., Bitto, E., Aceti, D.J., Phillips, G.N.
Proteins