CATH Classification

Domain Context

CATH Clusters

Superfamily Kinesin motor domain
Functional Family Kinesin-like protein KIF11

Enzyme Information

UniProtKB Entries (1)

P52732
KIF11_HUMAN
Homo sapiens
Kinesin-like protein KIF11

PDB Structure

PDB 2Q2Z
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
Roecker, A.J., Coleman, P.J., Mercer, S.P., Schreier, J.D., Buser, C.A., Walsh, E.S., Hamilton, K., Lobell, R.B., Tao, W., Diehl, R.E., South, V.J., Davide, J.P., Kohl, N.E., Yan, Y., Kuo, L.C., Li, C., Fernandez-Metzler, C., Mahan, E.A., Prueksaritanont, T., Hartman, G.D.
Bioorg.Med.Chem.Lett.