CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O96013
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O96013
PAK4_HUMAN
Homo sapiens
Serine/threonine-protein kinase PAK 4

PDB Structure

PDB 2Q0N
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of human p21 activating kinase 4 (PAK4) in complex with a consensus peptide.
Filippakopoulos, P., Eswaran, J., Turnbull, A., Papagrigoriou, E., Pike, A.W., von Delft, F., Sundstrom, M., Edwards, A., Arrowsmith, C.H., Weigelt, J., Knapp, S.
To be Published