1 keywords

CATH Domain 2pw6A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.830 Protocatechuate 4,5-dioxygenase; Chain B
Homologous Superfamily 3.40.830.10 LigB-like

Domain Context

CATH Clusters

Superfamily LigB-like
Functional Family 4,5-DOPA dioxygenase extradiol

Enzyme Information

1.13.11.29
Stizolobate synthase.
based on mapping to UniProt P24197
L-dopa + O(2) = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.
-!- The intermediate product undergoes ring closure and oxidation, with NAD(P)(+) as acceptor, to stizolobic acid.

UniProtKB Entries (1)

P24197
YGID_ECOLI
Escherichia coli K-12
4,5-DOPA dioxygenase extradiol

PDB Structure

PDB 2PW6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12.
Newton, M.G., Takagi, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokayama, S., Li, Y., Chen, L., Zhu, J., Ruble, J., Liu, Z.J., Rose, J.P., Wang, B.-C.
To be Published