CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Orotate phosphoribosyltransferase

Enzyme Information

2.4.2.10
Orotate phosphoribosyltransferase.
based on mapping to UniProt P13298
Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23.

UniProtKB Entries (1)

P13298
PYRE_YEAST
Saccharomyces cerevisiae S288C
Orotate phosphoribosyltransferase 1

PDB Structure

PDB 2PRY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase.
Gonzalez-Segura, L., Witte, J.F., McClard, R.W., Hurley, T.D.
Biochemistry