CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.40 | Phosphatase 2c; domain 1 |
|
3.60.40.10 | PPM-type phosphatase domain |
Domain Context
CATH Clusters
| Superfamily | PPM-type phosphatase domain |
| Functional Family | Pyruvate dehyrogenase phosphatase catalytic subunit 1 |
Enzyme Information
| 3.1.3.43 |
[Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
based on mapping to UniProt O88483
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.
-!- A mitochondrial enzyme associated with EC 1.2.4.1 in the pyruvate dehydrogenase complex.
|
UniProtKB Entries (1)
| O88483 |
PDP1_RAT
Rattus norvegicus
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
|
PDB Structure
| PDB | 2PNQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications.
J.Mol.Biol.
|