CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.300.30
Functional Family Acetyl-coenzyme A synthetase, cytoplasmic

Enzyme Information

6.2.1.1
Acetate--CoA ligase.
based on mapping to UniProt Q8ZKF6
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
-!- Also acts on propanoate and propenoate.

UniProtKB Entries (1)

Q8ZKF6
ACSA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Acetyl-coenzyme A synthetase

PDB Structure

PDB 2P2B
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase.
Reger, A.S., Carney, J.M., Gulick, A.M.
Biochemistry