CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.5.140
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q9ZHF6
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q9ZHF6
DPO3_THEMA
Thermotoga maritima MSB8
DNA polymerase III PolC-type

PDB Structure

PDB 2P1J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a polC-type DNA polymerase III exonuclease domain from Thermotoga maritima
Bonanno, J.B., Rutter, M., Bain, K.T., Izuka, M., Sridhar, V., Smith, D., Wasserman, S., Sauder, J.M., Burley, S.K., Almo, S.C.
To be Published