CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Ribosomal RNA small subunit methyltransferase J

Enzyme Information

2.1.1.242
16S rRNA (guanine(1516)-N(2))-methyltransferase.
based on mapping to UniProt Q7UAV7
S-adenosyl-L-methionine + guanine(1516) in 16S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(1516) in 16S rRNA.
-!- The enzyme specifically methylates guanine(1516) at N(2) in 16S rRNA.

UniProtKB Entries (1)

Q7UAV7
RSMJ_SHIFL
Shigella flexneri
Ribosomal RNA small subunit methyltransferase J

PDB Structure

PDB 2OYR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of UPF0341 Protein (yhiQ) from Shigella flexneri in complex with S-Adenosyl Homocysteine, Northeast Structural Genomics Target SfR275
Forouhar, F., Su, M., Seetharaman, J., Janjua, H., Fang, Y., Xiao, R., Baran, M.C., Liu, J., Acton, T.B., Montelione, G.T., Tong, L., Hunt, J.F.
To be Published