CATH Classification

Domain Context

CATH Clusters

Superfamily main proteinase (3clpro) structure, domain 3
Functional Family Replicase polyprotein 1a

Enzyme Information

UniProtKB Entries (1)

Q6T1E9
Q6T1E9_CVHSA
SARS coronavirus CUHK-L2
Orf1ab polyprotein

PDB Structure

PDB 2OP9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Substrate Specificity Profiling and Identification of a New Class of Inhibitor for the Major Protease of the SARS Coronavirus.
Goetz, D.H., Choe, Y., Hansell, E., Chen, Y.T., McDowell, M., Jonsson, C.B., Roush, W.R., McKerrow, J., Craik, C.S.
Biochemistry