CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
Functional Family Ferredoxin--NADP reductase, apicoplast

Enzyme Information

1.18.1.2
Ferredoxin--NADP(+) reductase.
based on mapping to UniProt C6KT68
2 reduced ferredoxin + NADP(+) + H(+) = 2 oxidized ferredoxin + NADPH.
-!- In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin. -!- Formerly EC 1.6.7.1 and EC 1.6.99.4.

UniProtKB Entries (1)

C6KT68
FENR_PLAF7
Plasmodium falciparum 3D7
Ferredoxin--NADP reductase, apicoplast

PDB Structure

PDB 2OK8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis.
Milani, M., Balconi, E., Aliverti, A., Mastrangelo, E., Seeber, F., Bolognesi, M., Zanetti, G.
J.Mol.Biol.