CATH Classification

Domain Context

CATH Clusters

Superfamily RuBisCO large subunit, N-terminal domain
Functional Family

Enzyme Information

5.3.2.5
2,3-diketo-5-methylthiopentyl-1-phosphate enolase.
based on mapping to UniProt Q5L1E2
5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3- oxopent-1-enyl phosphate.
-!- The enzyme participates in the methionine salvage pathway in Bacillus subtilis. -!- In some species a single bifunctional enzyme, EC 3.1.3.77, catalyzes both this reaction and that of EC 3.1.3.87. -!- Formerly EC 5.3.2.n1.

UniProtKB Entries (1)

Q5L1E2
MTNW_GEOKA
Geobacillus kaustophilus HTA426
2,3-diketo-5-methylthiopentyl-1-phosphate enolase

PDB Structure

PDB 2OEK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mechanistic Diversity in the RuBisCO Superfamily: The "Enolase" in the Methionine Salvage Pathway in Geobacillus kaustophilus.
Imker, H.J., Fedorov, A.A., Fedorov, E.V., Almo, S.C., Gerlt, J.A.
Biochemistry