CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.1
Carboxylesterase.
based on mapping to UniProt Q0ZPV7
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
-!- Wide specificity; also hydrolyzes vitamin A esters. -!- The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4 and EC 3.5.1.13. -!- Formerly EC 3.1.1.12.

UniProtKB Entries (1)

Q0ZPV7
CXE1_ACTER
Actinidia eriantha
Carboxylesterase 1

PDB Structure

PDB 2O7R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon.
Ileperuma, N.R., Marshall, S.D., Squire, C.J., Baker, H.M., Oakeshott, J.G., Russell, R.J., Plummer, K.M., Newcomb, R.D., Baker, E.N.
Biochemistry