CATH Domain 2o7qA02

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10860	Leucine Dehydrogenase, chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Leucine Dehydrogenase, chain A, domain 1
Functional Family	Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

Enzyme Information

4.2.1.10	3-dehydroquinate dehydratase. based on mapping to UniProt Q9SQT8 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1.1.1.25	Shikimate dehydrogenase. based on mapping to UniProt Q9SQT8 Shikimate + NADP(+) = 3-dehydroshikimate + NADPH. -!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

DHQSD_ARATH

Arabidopsis thaliana

Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

PDB Structure

PDB	2O7Q
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The DHQ-dehydroshikimate-SDH-shikimate-NADP(H) Complex: Insights into Metabolite Transfer in the Shikimate Pathway Singh, S.A., Christendat, D. Cryst.Growth Des.