CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt Q8YGH2
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

Q8YGH2
RISB1_BRUME
Brucella melitensis bv. 1 str. 16M
6,7-dimethyl-8-ribityllumazine synthase 1

PDB Structure

PDB 2O6H
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
Klinke, S., Zylberman, V., Bonomi, H.R., Haase, I., Guimaraes, B.G., Braden, B.C., Bacher, A., Fischer, M., Goldbaum, F.A.
J.Mol.Biol.