CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Hexokinase 1

Enzyme Information

2.7.1.1
Hexokinase.
based on mapping to UniProt P52789
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.

UniProtKB Entries (1)

P52789
HXK2_HUMAN
Homo sapiens
Hexokinase-2

PDB Structure

PDB 2NZT
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human hexokinase II
Rabeh, W.M., Zhu, H., Nedyalkova, L., Tempel, W., Wasney, G., Landry, R., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H.
To be Published