1 keywords

CATH Domain 2nv5A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.190 Protein-Tyrosine Phosphatase; Chain A
Homologous Superfamily 3.90.190.10 Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Receptor-type tyrosine-protein phosphatase F isoform A

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q64605
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q64605
PTPRS_RAT
Rattus norvegicus
Receptor-type tyrosine-protein phosphatase S

PDB Structure

PDB 2NV5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural genomics of protein phosphatases.
Almo, S.C., Bonanno, J.B., Sauder, J.M., Emtage, S., Dilorenzo, T.P., Malashkevich, V., Wasserman, S.R., Swaminathan, S., Eswaramoorthy, S., Agarwal, R., Kumaran, D., Madegowda, M., Ragumani, S., Patskovsky, Y., Alvarado, J., Ramagopal, U.A., Faber-Barata, J., Chance, M.R., Sali, A., Fiser, A., Zhang, Z.Y., Lawrence, D.S., Burley, S.K.
J.STRUCT.FUNCT.GENOM.