CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P81065
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P81065
GST_OCHAN
Ochrobactrum anthropi
Glutathione S-transferase

PDB Structure

PDB 2NTO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Role of Ser11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase
Federici, L., Masulli, M., Bonivento, D., Di Matteo, A., Gianni, S., Favaloro, B., Di Ilio, C., Allocati, N.
Biochem.J.