CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family NH(3)-dependent NAD(+) synthetase

Enzyme Information

6.3.1.5
NAD(+) synthase.
based on mapping to UniProt P08164
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
-!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).

UniProtKB Entries (1)

P08164
NADE_BACSU
Bacillus subtilis subsp. subtilis str. 168
NH(3)-dependent NAD(+) synthetase

PDB Structure

PDB 2NSY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure.
Rizzi, M., Bolognesi, M., Coda, A.
Structure