CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaconate Coenzyme A-transferase
Functional Family Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial

Enzyme Information

2.8.3.5
3-oxoacid CoA-transferase.
based on mapping to UniProt Q29551
Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.
-!- Acetoacetate or, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor. -!- Malonyl-CoA can act instead of succinyl-CoA.

UniProtKB Entries (1)

Q29551
SCOT1_PIG
Sus scrofa
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

PDB Structure

PDB 2NRB
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification of the Cysteine Residue Exposed by the Conformational Change in Pig Heart Succinyl-CoA:3-Ketoacid Coenzyme A Transferase on Binding Coenzyme A.
Tammam, S.D., Rochet, J.C., Fraser, M.E.
Biochemistry