CATH Domain 2nq8C00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.400	Enoyl acyl carrier protein reductase

Domain Context

CATH Clusters

Superfamily	Enoyl acyl carrier protein reductase
Functional Family	Enoyl-[acyl-carrier-protein] reductase [NADH]

Enzyme Information

UniProtKB Entries (1)

Q9BJJ9_PLAFA

Plasmodium falciparum

Enoyl-ACP reductase

PDB Structure

PDB	2NQ8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy Freundlich, J.S., Wang, F., Tsai, H.C., Kuo, M., Shieh, H.M., Anderson, J.W., Nkrumah, L.J., Valderramos, J.C., Yu, M., Kumar, T.R., Valderramos, S.G., Jacobs, W.R., Schiehser, G.A., Jacobus, D.P., Fidock, D.A., Sacchettini, J.C. J.Biol.Chem.