CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P67775
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

Q13362
2A5G_HUMAN
Homo sapiens
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

PDB Structure

PDB 2NPP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the protein phosphatase 2A holoenzyme
Xu, Y., Xing, Y., Chen, Y., Chao, Y., Lin, Z., Fan, E., Yu, J.W., Strack, S., Jeffrey, P.D., Shi, Y.
Cell(Cambridge,Mass.)