CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family Putative potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

Enzyme Information

UniProtKB Entries (1)

Q9Y3Q4
HCN4_HUMAN
Homo sapiens
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

PDB Structure

PDB 2MNG
External Links
Method SOLUTION NMR
Organism
Primary Citation
A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.
Akimoto, M., Zhang, Z., Boulton, S., Selvaratnam, R., VanSchouwen, B., Gloyd, M., Accili, E.A., Lange, O.F., Melacini, G.
J.Biol.Chem.