CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt Q6ITZ3
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

Q6ITZ3
ML4_VISAL
Viscum album
Beta-galactoside-specific lectin 4

PDB Structure

PDB 2MLL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of mistletoe lectin I from Viscum album.
Krauspenhaar, R., Eschenburg, S., Perbandt, M., Kornilov, V., Konareva, N., Mikailova, I., Stoeva, S., Wacker, R., Maier, T., Singh, T., Mikhailov, A., Voelter, W., Betzel, C.
Biochem.Biophys.Res.Commun.