CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Vav guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (2)

P48025
KSYK_MOUSE
Mus musculus
Tyrosine-protein kinase SYK
P15498
VAV_HUMAN
Homo sapiens
Proto-oncogene vav

PDB Structure

PDB 2MC1
External Links
Method SOLUTION NMR
Organism
Primary Citation
Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain.
Chen, C.H., Piraner, D., Gorenstein, N.M., Geahlen, R.L., Beth Post, C.
Biopolymers