CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonucleoside hydrolase-like
Functional Family

Enzyme Information

3.2.2.2
Inosine nucleosidase.
based on mapping to UniProt Q27546
Inosine + H(2)O = D-ribose + hypoxanthine.
3.2.2.3
Uridine nucleosidase.
based on mapping to UniProt Q27546
Uridine + H(2)O = D-ribose + uracil.

UniProtKB Entries (1)

Q27546
IUNH_CRIFA
Crithidia fasciculata
Inosine-uridine preferring nucleoside hydrolase

PDB Structure

PDB 2MAS
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor.
Degano, M., Almo, S.C., Sacchettini, J.C., Schramm, V.L.
Biochemistry