CATH Classification

Domain Context

CATH Clusters

Superfamily Coactivator CBP, KIX domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q92793
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

Q92793
CBP_HUMAN
Homo sapiens
CREB-binding protein

PDB Structure

PDB 2LXS
External Links
Method SOLUTION NMR
Organism
Primary Citation
Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core.
Bruschweiler, S., Konrat, R., Tollinger, M.
Acs Chem.Biol.