CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P45481
CBP_MOUSE
Mus musculus
CREB-binding protein

PDB Structure

PDB 2LWW
External Links
Method SOLUTION NMR
Organism
Primary Citation
Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-kappa B-Driven Transcription.
Mukherjee, S.P., Behar, M., Birnbaum, H.A., Hoffmann, A., Wright, P.E., Ghosh, G.
Plos Biol.