CATH Domain 2lq7A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.290	Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A
	3.10.290.20	Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3

Domain Context

CATH Clusters

Superfamily	Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3
Functional Family	NEDD8-activating enzyme E1 catalytic subunit, variant

Enzyme Information

6.2.1.-

Acid--thiol ligases.

based on mapping to UniProt Q8TBC4

UniProtKB Entries (1)

UBA3_HUMAN

Homo sapiens

NEDD8-activating enzyme E1 catalytic subunit

PDB Structure

PDB	2LQ7
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	E2-binding surface on Uba3 beta-grasp domain undergoes a conformational transition. Elgin, E.S., Sokmen, N., Peterson, F.C., Volkman, B.F., Dag, C., Haas, A.L. Proteins