CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.287.2920
Functional Family RNA polymerase II holoenzyme complex component

Enzyme Information

UniProtKB Entries (1)

P19659
MED15_YEAST
Saccharomyces cerevisiae S288C
Mediator of RNA polymerase II transcription subunit 15

PDB Structure

PDB 2LPB
External Links
Method SOLUTION NMR
Organism
Primary Citation
The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Brzovic, P.S., Heikaus, C.C., Kisselev, L., Vernon, R., Herbig, E., Pacheco, D., Warfield, L., Littlefield, P., Baker, D., Klevit, R.E., Hahn, S.
Mol.Cell
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