CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family L-lactate dehydrogenase A chain

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P00342
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P00342
LDHC_MOUSE
Mus musculus
L-lactate dehydrogenase C chain

PDB Structure

PDB 2LDX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of the antigenic sites on the refined 3-A resolution structure of mouse testicular lactate dehydrogenase C4.
Hogrefe, H.H., Griffith, J.P., Rossmann, M.G., Goldberg, E.
J.Biol.Chem.