CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.240
Functional Family SBDS ribosome maturation factor

Enzyme Information

UniProtKB Entries (1)

Q9Y3A5
SBDS_HUMAN
Homo sapiens
Ribosome maturation protein SBDS

PDB Structure

PDB 2L9N
External Links
Method SOLUTION NMR
Organism
Primary Citation
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.
Finch, A.J., Hilcenko, C., Basse, N., Drynan, L.F., Goyenechea, B., Menne, T.F., Gonzalez Fernandez, A., Simpson, P., D'Santos, C.S., Arends, M.J., Donadieu, J., Bellanne-Chantelot, C., Costanzo, M., Boone, C., McKenzie, A.N., Freund, S.M., Warren, A.J.
Genes Dev.