CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family Lamin B receptor

Enzyme Information

1.3.1.70
Delta(14)-sterol reductase.
based on mapping to UniProt P23913
4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NADP(+) = 4,4- dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol + NADPH.
-!- Acts on a range of steroids with a 14(15)-double bond.

UniProtKB Entries (1)

P23913
LBR_CHICK
Gallus gallus
Delta(14)-sterol reductase

PDB Structure

PDB 2L8D
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure and molecular interactions of lamin B receptor tudor domain.
Liokatis, S., Edlich, C., Soupsana, K., Giannios, I., Panagiotidou, P., Tripsianes, K., Sattler, M., Georgatos, S.D., Politou, A.S.
J.Biol.Chem.