CATH Classification

Domain Context

CATH Clusters

Superfamily 5' to 3' exonuclease, C-terminal subdomain
Functional Family DNA repair endonuclease XPF isoform X2

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt Q92889

UniProtKB Entries (1)

Q92889
XPF_HUMAN
Homo sapiens
DNA repair endonuclease XPF

PDB Structure

PDB 2KN7
External Links
Method SOLUTION NMR
Organism
Primary Citation
The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition
Das, D., Folkers, G.E., van Dijk, M., Jaspers, N.G.J., Hoeijmakers, J.H.J., Kaptein, R., Boelens, R.
Structure