CATH Classification

Domain Context

CATH Clusters

Superfamily Zinc/RING finger domain, C3HC4 (zinc finger)
Functional Family Lysine (K)-specific demethylase 5A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt P29375

UniProtKB Entries (1)

P29375
KDM5A_HUMAN
Homo sapiens
Lysine-specific demethylase 5A

PDB Structure

PDB 2KGG
External Links
Method SOLUTION NMR
Organism
Primary Citation
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Wang, G.G., Song, J., Wang, Z., Dormann, H.L., Casadio, F., Li, H., Luo, J.L., Patel, D.J., Allis, C.D.
Nature