CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.3830 | Diacylglycerol kinase fold |
|
1.10.3830.10 | Diacylglycerol kinase (DAGK) domain |
Domain Context
CATH Clusters
| Superfamily | Diacylglycerol kinase (DAGK) domain |
| Functional Family |
Enzyme Information
| 2.7.1.107 |
Diacylglycerol kinase (ATP).
based on mapping to UniProt P0ABN1
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.
|
UniProtKB Entries (1)
| P0ABN1 |
KDGL_ECOLI
Escherichia coli K-12
Diacylglycerol kinase
|
PDB Structure
| PDB | 2KDC |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase
Science
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