1 keywords

CATH Domain 2ka6B00

CATH Classification

Level CATH Code Description
Class 6 Special
Architecture 6.10 Helix non-globular
Topology 6.10.250 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous Superfamily 6.10.250.3310 signal transducer and activator of transcription 1

Domain Context

CATH Clusters

Superfamily signal transducer and activator of transcription 1
Functional Family Signal transducer and activator of transcription

Enzyme Information

UniProtKB Entries (2)

P45481
CBP_MOUSE
Mus musculus
CREB-binding protein
P42224
STAT1_HUMAN
Homo sapiens
Signal transducer and activator of transcription 1-alpha/beta

PDB Structure

PDB 2KA6
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.
Wojciak, J.M., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
Embo J.