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1 keywords

CATH Domain 2k2wA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.10980 Nibrin, BRCT2 domain

Domain Context

CATH Clusters

Superfamily Nibrin, BRCT2 domain
Functional Family Nibrin

Enzyme Information

UniProtKB Entries (1)

Q6XV80
Q6XV80_XENLA
Xenopus laevis
Nibrin

PDB Structure

PDB 2K2W
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.
Xu, C., Wu, L., Cui, G., Botuyan, M.V., Chen, J., Mer, G.
J.Mol.Biol.
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