CATH Domain 2jw5A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10190	BRCT domain

Domain Context

CATH Clusters

Superfamily	BRCT domain
Functional Family	DNA polymerase

Enzyme Information

4.2.99.-	Other carbon-oxygen lyases. based on mapping to UniProt Q9UGP5
2.7.7.7	DNA-directed DNA polymerase. based on mapping to UniProt Q9UGP5 Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). -!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

DPOLL_HUMAN

Homo sapiens

DNA polymerase lambda

PDB Structure

PDB	2JW5
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Polymerase Lambda BRCT domain Mueller, G.A., Moon, A.F., DeRose, E.F., Davis, B.J., Ramsden, D.A., Pedersen, L.C., London, R.E. To be Published