CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1620.60
Functional Family A disintegrin and metalloproteinase with thrombospondin motifs 1

Enzyme Information

3.4.24.-
Metalloendopeptidases.
based on mapping to UniProt Q9UHI8

UniProtKB Entries (1)

Q9UHI8
ATS1_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 1

PDB Structure

PDB 2JIH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains.
Gerhardt, S., Hassall, G., Hawtin, P., McCall, E., Flavell, L., Minshull, C., Hargreaves, D., Ting, A., Pauptit, R.A., Parker, A.E., Abbott, W.M.
J. Mol. Biol.