CATH Classification

Domain Context

CATH Clusters

Superfamily acylaminoacyl peptidase
Functional Family

Enzyme Information

3.7.1.19
2,6-dihydroxypseudooxynicotine hydrolase.
based on mapping to UniProt Q93NG6
1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H(2)O = 2,6- dihydroxypyridine + 4-methylaminobutanoate.
-!- The enzyme, characterized from the soil bacterium Arthrobacter nicotinovorans, participates in nicotine degradation.

UniProtKB Entries (1)

Q93NG6
DHPON_PAENI
Paenarthrobacter nicotinovorans
2,6-dihydropseudooxynicotine hydrolase

PDB Structure

PDB 2JBW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Action of a Cc Bond Cleaving Alpha/Beta-Hydrolase Involved in Nicotine Degration.
Schleberger, C., Sachelaru, P., Brandsch, R., Schulz, G.E.
J.Mol.Biol.