CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.390.30
Functional Family Thioredoxin reductase 1, cytoplasmic

Enzyme Information

1.8.1.9
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q16881
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.

UniProtKB Entries (1)

Q16881
TRXR1_HUMAN
Homo sapiens
Thioredoxin reductase 1, cytoplasmic

PDB Structure

PDB 2J3N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of Human Thioredoxin Reductase 1 Provides Insights Into C-Terminal Rearrangements During Catalysis.
Fritz-Wolf, K., Urig, S., Becker, K.
J.Mol.Biol.