CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family

Enzyme Information

2.5.1.1
Dimethylallyltranstransferase.
based on mapping to UniProt Q43133
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
-!- Will not accept larger prenyl diphosphates as efficient donors.
2.5.1.-
Transferring alkyl or aryl groups, other than methyl groups.
based on mapping to UniProt Q43133
2.5.1.10
(2E,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt Q43133
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
-!- Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. -!- The enzyme will not accept larger prenyl diphosphates as efficient donors.
2.5.1.29
Geranylgeranyl diphosphate synthase.
based on mapping to UniProt Q43133
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
-!- Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

Q43133
GGPPS_SINAL
Sinapis alba
Geranylgeranyl pyrophosphate synthase, chloroplastic/chromoplastic

PDB Structure

PDB 2J1O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Reaction Geometry of Geranylgeranyl Diphosphate Synthase from Sinapis Alba.
Kloer, D.P., Welsch, R., Beyer, P., Schulz, G.E.
Biochemistry