CATH Classification
Domain Context
CATH Clusters
| Superfamily | Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C |
| Functional Family | Thymidine phosphorylase |
Enzyme Information
| 2.4.2.4 |
Thymidine phosphorylase.
based on mapping to UniProt P19971
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.
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UniProtKB Entries (1)
| P19971 |
TYPH_HUMAN
Homo sapiens
Thymidine phosphorylase
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PDB Structure
| PDB | 2J0F |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for Non-Competitive Product Inhibition in Human Thymidine Phosphorylase: Implications for Drug Design.
Biochem.J.
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