CATH Classification

Domain Context

CATH Clusters

Superfamily Ferrodoxin-fold anticodon-binding domain
Functional Family Phenylalanine--tRNA ligase beta subunit

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt Q5SGX1
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

Q5SGX2
SYFA_THET8
Thermus thermophilus HB8
Phenylalanine--tRNA ligase alpha subunit

PDB Structure

PDB 2IY5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end.
Moor, N., Kotik-Kogan, O., Tworowski, D., Sukhanova, M., Safro, M.
Biochemistry